Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | BACE1 | P56817 | 3/20 | 0.46 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597887 | 0.88 | CHRM3 (0.42) | — | |
| SCHEMBL4596616 | 0.84 | CHRM3 (0.41) | — | |
| SCHEMBL4596041 | 0.76 | KDM4E (0.32) | MAPTALDH1A1BACE1PKM | |
| SCHEMBL445885 | 0.71 | ALDH1A1 (0.97) | KCNJ1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4597761 | 0.71 | KCNJ1 (0.44) | KCNJ1MAPTALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL16370438 | 0.70 | ALDH1A1 (0.94) | KCNJ1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14726057 | 0.70 | ALDH1A1 (1.00) | KCNJ1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5573713 | 0.70 | CCR5 (0.67) | — | |
| Hydrochloric Acid SCHEMBL29388956 | 0.69 | ALDH1A1 (0.97) | KCNJ1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5181129 | 0.69 | CXCR3 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |