Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 12/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 11/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597759 | 0.88 | KCNJ1 (0.51) | — | |
| SCHEMBL4596616 | 0.86 | CHRM3 (0.41) | CHRM3CHRM2CXCR3 | |
| SCHEMBL4597403 | 0.79 | CCR5 (0.52) | CHRM3CHRM2CXCR3 | |
| SCHEMBL4596041 | 0.78 | KDM4E (0.32) | CHRM3 | |
| SCHEMBL4597256 | 0.71 | DRD2 (0.34) | CXCR3 | |
| SCHEMBL5181129 | 0.71 | CXCR3 (0.48) | CHRM3CHRM2CXCR3 | |
| SCHEMBL4596625 | 0.69 | HTR2C (0.35) | CHRM3CHRM2 | |
| SCHEMBL4597890 | 0.69 | CXCR3 (0.39) | CHRM3CHRM2CXCR3NCF1 | |
| Benzylamine SCHEMBL27789840 | 0.68 | NCF1 (0.78) | NCF1 | |
| SCHEMBL5572519 | 0.67 | CCR5 (0.72) | CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |