Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 4/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470805 | 0.89 | DPP4 (0.32) | PIK3R1PIK3CARETDPP4DPP8 | |
| SCHEMBL458011 | 0.81 | ACACB (0.35) | ACACBGPR119RETDPP4DPP8 | |
| SCHEMBL457629 | 0.80 | GPR119 (0.35) | ACACBGPR119RETSCN9ADPP4 | |
| SCHEMBL470475 | 0.76 | GPR119 (0.38) | ACACBGPR119DPP4DPP8DPP9 | |
| SCHEMBL12064854 | 0.75 | DPP4 (0.31) | DPP4 | |
| SCHEMBL12064617 | 0.75 | DPP4 (0.31) | DPP4 | |
| SCHEMBL470590 | 0.74 | NTRK1 (0.38) | ACACBGPR119RET | |
| SCHEMBL462498 | 0.74 | RET (0.40) | GPR119RETDPP4DPP8DPP9 | |
| SCHEMBL12064792 | 0.74 | GPR119 (0.45) | ACACBGPR119 | |
| SCHEMBL460034 | 0.74 | CHRM2 (0.38) | ACACBRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |