Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598388 | 0.80 | ADORA1 (0.34) | ADORA1KDM4EATM | |
| SCHEMBL4938159 | 0.78 | CHRM5 (0.40) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL2274453 | 0.76 | CASP3 (0.47) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| Tetrahydrofuran SCHEMBL15556365 | 0.71 | CASP3 (0.42) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL2910520 | 0.70 | LMNA (0.48) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL4598439 | 0.70 | CASP3 (0.41) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL4598109 | 0.70 | TACR1 (0.35) | MAPTLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL17488514 | 0.69 | CHRM5 (0.65) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL20670367 | 0.68 | CASP3 (0.52) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL15415970 | 0.68 | CASP3 (0.54) | CHRM5CHRM1CHRM2CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908471-A1 | Tetrahydropyridines as renin inhibitors | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |