Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 10/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 8/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598320 | 0.78 | CHRM5 (0.38) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL2274453 | 0.72 | CASP3 (0.47) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL4934280 | 0.71 | NR1H2 (0.41) | ADORA1ALDH1A1 | |
| SCHEMBL4939031 | 0.69 | REN (0.44) | — | |
| Tetrahydrofuran SCHEMBL15556365 | 0.69 | CASP3 (0.42) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL4598439 | 0.68 | CASP3 (0.41) | CHRM5CHRM1CHRM2CHRM4CHRM3 | |
| Alcohol SCHEMBL8697373 | 0.67 | IDO1 (0.47) | CHRM1CHRM2MEN1KMT2ALMNA | |
| SCHEMBL4938707 | 0.67 | NR1H2 (0.37) | PKM | |
| SCHEMBL2252126 | 0.67 | IDO1 (0.53) | MEN1KMT2ALMNAL3MBTL1POLB | |
| SCHEMBL2910520 | 0.67 | LMNA (0.48) | CHRM5CHRM1CHRM2CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234305-A1 | Novel Tetrahydropyridine Derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234305-A1 | Novel Tetrahydropyridine Derivatives | REN, AGTR1, CBR1 | CHRM5 30/4885CHRM1 13/4885CHRM2 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.