Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4599615 | 0.79 | LMNA (0.36) | HPGDALDH1A1LMNAKMT2AL3MBTL1 | |
| SCHEMBL4600271 | 0.79 | LMNA (0.42) | HPGDCYP1A2CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL4600236 | 0.76 | EGFR (0.34) | POLBALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL6002123 | 0.73 | SMN1; SMN2 (0.39) | HPGDCYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL4599766 | 0.72 | MAPT (0.41) | POLBALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL168718 | 0.72 | ALDH1A1 (0.38) | HPGDCYP1A2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4295987 | 0.70 | MAPT (0.48) | HPGDCYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL4603282 | 0.70 | PKM (0.42) | HPGDSMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL4598887 | 0.69 | CA12 (0.35) | HPGDALDH1A1KDM4EGAACA12 | |
| SCHEMBL197458 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910320-A2 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007011065-A2 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-01-25 | — | — | WO | disclosed |