SCHEMBL9655468

SCHEMBL9655468

O=C(CF)C(F)(F)C(=O)c1ccccc1.O=C(CF)C(F)(F)C(=O)c1ccccc1.O=C(CF)C(F)(F)C(=O)c1ccccc1.O=C(CF)C(F)(F)C(=O)c1ccccc1.[Eu]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 7/20 0.55
MAPK1 P28482 3/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
F2 P00734 1/20 0.39
LMNA P02545 1/20 0.39
ALDH1A1 P00352 3/20 0.38
CES2 O00748 2/20 0.38
DAO P14920 1/20 0.38
TSHR P16473 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
PTPN1 P18031 2/20 0.38
SRC P12931 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9630805 1.00 CES1 (0.55) CES1MAPK1KDM4EMEN1CYP3A4
SCHEMBL583437 0.98 CES1 (0.57) CES1MAPK1KDM4EMEN1CYP3A4
SCHEMBL9565947 0.96 CES1 (0.55) CES1MAPK1KDM4EMEN1CYP3A4
SCHEMBL9770760 0.87 CES1 (0.46) CES1KDM4EMAPTHPGDSMN1; SMN2
Phenanthroline SCHEMBL3130837 0.83 LMNA (0.43) CES1KDM4EMEN1CYP3A4MAPT
SCHEMBL7907262 0.81 CES1 (0.73) CES1MAPK1KDM4EMEN1CYP3A4
SCHEMBL711848 0.81 PLOD2 (0.50) CES1KMT2ACES2PTPN1MLYCD
SCHEMBL583454 0.79 CES1 (0.43) CES1MAPTHPGDTDP1LMNA
SCHEMBL2851867 0.79 PLOD2 (0.51) KDM4EMEN1CYP3A4HPGDKMT2A
SCHEMBL584064 0.79 CES2 (0.43) CES1MAPK1KDM4EMAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5079429-A Optical characteristic adjusting apparatus PIONEER ELECTRONIC CORPORATION (JP) 1992-01-07 US claimed
JP-63191870-A None JP disclosed
US-5079429-A Optical characteristic adjusting apparatus PIONEER ELECTRONIC CORPORATION (JP) 1992-01-07 US disclosed
JP-S63191870-A LUMINESCENT INK COMPOSITION MITSUI TOATSU CHEM INC 1988-08-09 JP disclosed