Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.57 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MDM4 | O15151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1637302 | 0.87 | KMT2A (0.55) | CASP3MDM2KMT2AMDM4TP53 | |
| SCHEMBL29386346 | 0.86 | CASP3 (0.57) | CASP3MDM2KMT2AMDM4TP53 | |
| SCHEMBL29511158 | 0.86 | CASP3 (0.52) | CASP3MDM2KMT2AMDM4TP53 | |
| SCHEMBL2313063 | 0.86 | CASP3 (0.57) | CASP3MDM2KMT2AMDM4TP53 | |
| SCHEMBL8350965 | 0.86 | CASP3 (0.52) | CASP3MDM2KMT2AMDM4TP53 | |
| SCHEMBL29423514 | 0.86 | CASP3 (0.57) | CASP3MDM2KMT2AMDM4TP53 | |
| SCHEMBL7423417 | 0.86 | CASP3 (0.57) | CASP3MDM2KMT2AMDM4TP53 | |
| SCHEMBL13163967 | 0.86 | CASP3 (0.57) | CASP3MDM2KMT2AMDM4TP53 | |
| SCHEMBL29361981 | 0.86 | CASP3 (0.57) | CASP3MDM2KMT2AMDM4TP53 | |
| SCHEMBL5058092 | 0.86 | CASP3 (0.51) | CASP3MDM2KMT2AMDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008080223-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE | MIGENIX INC. (CA) | 2008-07-10 | — | — | WO | disclosed |
| EP-1910279-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007002639-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2007-01-04 | — | — | WO | disclosed |