Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598759 | 0.88 | TAS1R3 (0.38) | CYP1A2CYP2C9CYP2C19KMT2ANPSR1 | |
| SCHEMBL4720153 | 0.76 | ACP3 (0.39) | KMT2AFDPSALDH1A1 | |
| SCHEMBL11076433 | 0.76 | CYP1A2 (0.67) | CYP1A2CYP2C9CYP2C19KMT2ANPSR1 | |
| SCHEMBL11145386 | 0.68 | FDPS (0.80) | CYP1A2CYP2C9CYP2C19KMT2ANPSR1 | |
| SCHEMBL2637102 | 0.68 | NPSR1 (0.42) | CYP1A2CYP2C9CYP2C19KMT2ANPSR1 | |
| SCHEMBL6656697 | 0.67 | PPARG (0.61) | CYP1A2CYP2C9CYP2C19KMT2ANPSR1 | |
| SCHEMBL14379934 | 0.67 | CYP1A2 (0.51) | CYP1A2CYP2C9CYP2C19KMT2ANPSR1 | |
| SCHEMBL13538704 | 0.67 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19KMT2ANPSR1 | |
| SCHEMBL13955907 | 0.66 | PPARG (0.55) | CYP1A2CYP2C9CYP2C19KMT2ANPSR1 | |
| SCHEMBL28063668 | 0.66 | ACHE (0.65) | CYP1A2CYP2C9CYP2C19KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910309-A2 | CYCLOALKYL AMINO-HYDANTOIN COMPOUNDS AND USE THEREOF FOR ß-SECRETASE MODULATION | Wyeth (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007016012-A2 | CYCLOALKYL AMINO-HYDANTOIN COMPOUNDS AND USE THEREOF FOR β-SECRETASE MODULATION | WYETH (US) | 2007-02-08 | — | — | WO | disclosed |