Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4599288 | 0.76 | CYP1A2 (0.48) | ALDH1A1KMT2AFDPS | |
| SCHEMBL4598759 | 0.74 | TAS1R3 (0.38) | ACP3KMT2AFDPS | |
| SCHEMBL1651816 | 0.69 | ACP3 (0.41) | ACP3ALDH1A1KMT2A | |
| SCHEMBL6449523 | 0.67 | ACP3 (0.39) | ACP3ALDH1A1KMT2AFDPSMEN1 | |
| SCHEMBL13190171 | 0.66 | CYP26A1 (0.37) | ALDH1A1KMT2ASTAT1TNF | |
| SCHEMBL13189607 | 0.66 | ALDH1A1 (0.36) | ALDH1A1TNF | |
| SCHEMBL12412508 | 0.66 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL6327854 | 0.65 | ACP3 (0.61) | ACP3ALDH1A1CA12MMP2CA9 | |
| SCHEMBL9709122 | 0.64 | ALDH1A1 (0.38) | ALDH1A1KMT2A | |
| SCHEMBL28456024 | 0.64 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |