Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL672311 | 0.76 | THRB (0.36) | GLAHRH3CYP1A2ALDH1A1PKM | |
| SCHEMBL2704549 | 0.73 | — | — | |
| SCHEMBL2749618 | 0.73 | AGL (0.33) | TDP1 | |
| SCHEMBL29044106 | 0.72 | HRH3 (0.48) | GLAHRH3MAPK1CYP1A2SMN1; SMN2 | |
| Propane SCHEMBL1998876 | 0.69 | THRB (0.40) | GLAHRH3CYP1A2ALDH1A1PKM | |
| SCHEMBL18154865 | 0.69 | THRB (0.35) | GLAHRH3MAPK1CYP1A2SMN1; SMN2 | |
| SCHEMBL9489055 | 0.69 | HRH3 (0.60) | HRH3 | |
| SCHEMBL1535860 | 0.69 | THRB (0.35) | GLAHRH3MAPK1CYP1A2SMN1; SMN2 | |
| SCHEMBL12809484 | 0.69 | HRH3 (0.60) | HRH3 | |
| SCHEMBL23754292 | 0.69 | AGL (0.33) | MAPK1ALDH1A1KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080089932-A1 | Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | MARINA BIOTECH, INC. | 2008-04-17 | — | — | US | claimed |
| US-20160151282-A1 | AMPHOTERIC LIPOSOME FORMULATIONS | MARINA BIOTECH INC (US) | 2016-06-02 | — | — | US | disclosed |
| US-9283186-B2 | Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | MARINA BIOTECH, INC. (US) | 2016-03-15 | — | — | US | disclosed |
| EP-2462924-A2 | Improvements in or relating to amphoteric liposomes. | Marina Biotech, Inc. (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20120135065-A1 | Amphoteric Liposomes, A Method Of Formulating An Amphoteric Liposome And A Method Of Loading An Amphoteric Liposome | MARINA BIOTECH, INC. | 2012-05-31 | — | — | US | disclosed |
| US-20080089932-A1 | Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | MARINA BIOTECH, INC. | 2008-04-17 | — | — | US | disclosed |
| EP-1911443-A1 | Amphoteric liposomes, method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | Novosom AG (DE) | 2008-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135065-A1 | Amphoteric Liposomes, A Method Of Formulating An Amphoteric Liposome And A Method Of Loading An Amphoteric Liposome | LIPA, SGMS1, SGMS2 | GLA 1447/4885HRH3 1082/4885MAPK1 4068/4885 |
| US-20160151282-A1 | AMPHOTERIC LIPOSOME FORMULATIONS | LIPA, SGMS1, SGMS2 | GLA 2036/4885HRH3 1030/4885MAPK1 4264/4885 |
| US-20080089932-A1 | Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | LIPA, SGMS1, SGMS2 | GLA 1447/4885HRH3 1082/4885MAPK1 4068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.