SCHEMBL4599771

SCHEMBL4599771

CC1CC(C)(C)CC(=O)C1=O

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.41
KDM4E B2RXH2 3/20 0.41
GAA P10253 3/20 0.41
GLA P06280 1/20 0.41
MAPT P10636 5/20 0.38
POLB P06746 2/20 0.38
MAOA P21397 1/20 0.35
HSD17B10 Q99714 2/20 0.34
HTT P42858 4/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALPL P05186 1/20 0.33
NCOA1 Q15788 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
HPGD P15428 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3503955 1.00 ALDH1A1 (0.41) ALDH1A1KDM4EGAAGLAMAPT
SCHEMBL16777663 0.76 MAPT (0.43) ALDH1A1KDM4EGAAGLAMAPT
SCHEMBL108518 0.75
SCHEMBL21247206 0.75
SCHEMBL11260074 0.73 MAPT (0.32) ALDH1A1KDM4EMAPTPOLBTSHR
SCHEMBL11260079 0.73 MAPT (0.32) ALDH1A1KDM4EMAPTPOLBTSHR
SCHEMBL11268397 0.73 ALDH1A1 (0.36) ALDH1A1KDM4EGAAGLAMAPT
SCHEMBL11268392 0.73 ALDH1A1 (0.36) ALDH1A1KDM4EGAAGLAMAPT
SCHEMBL15727994 0.67 MAPT (0.43) ALDH1A1KDM4EGAAGLAMAPT
SCHEMBL2324941 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113663463-B Odor inhibitor 日东生物科技(浙江)有限公司 2022-08-02 CN claimed
CN-110568101-B Method for determining volatile and semi-volatile components in cut tobacco based on HS-SPME-GC-MS/MS 云南中烟工业有限责任公司 2022-04-01 CN claimed
CN-113663463-A Odor inhibitor 日东生物科技(浙江)有限公司 2021-11-19 CN claimed
US-10920176-B2 Transparent liquids, in particular fabric treatment agents, comprising perfume and microcapsules with an odor modulator compound HENKEL AG & CO. KGAA (DE) 2021-02-16 US claimed
CN-112220095-A Cigarette production method based on temperature of moisture regain area and cigarette 云南中烟工业有限责任公司 2021-01-15 CN claimed
CN-110568101-A Method for determining volatile and semi-volatile components in cut tobacco based on HS-SPME-GC-MS/MS 云南中烟工业有限责任公司 2019-12-13 CN claimed
CN-110554112-A method for judging quality of fen-flavor cigarettes CHINA TOBACCO YUNNAN IND CO LTD 2019-12-10 CN claimed
CN-108929400-A A kind of nickel catalyst system, high-performance polybutadiene and preparation method thereof 北京化工大学 2018-12-04 CN claimed
EP-3350296-A1 PERFUME COMPOSITION COMPRISING AN ODOR MODULATOR COMPOUND, AMINO ALCOHOL AND ODORIFEROUS ALDEHYDE AND/OR ODORIFEROUS KETONE FOR INCREASING AND PROLONGING ODOR INTENSITY Henkel AG & Co. KGaA (DE) 2018-07-25 EP claimed
EP-3349861-A1 PERFUME COMPOSITION COMPRISING FRAGRANCE MODULATOR COMPOUNDS AND SILICIC ACID ESTERS FOR INCREASING AND PROLONGING THE INTENSITY OF FRAGRANCE Henkel AG & Co. KGaA (DE) 2018-07-25 EP claimed
WO-2017046055-A1 PERFUME COMPOSITIONS COMPRISING MICROCAPSULES, FRAGRANCE MODULATOR COMPOUNDS AND FRAGRANCE RAW MATERIAL FOR INCREASING AND PROLONGING THE INTENSITY OF FRAGRANCE HENKEL AG & CO. KGAA (DE) 2017-03-23 WO claimed
WO-2017046054-A1 PERFUME COMPOSITION COMPRISING AN ODOR MODULATOR COMPOUND, AMINO ALCOHOL AND ODORIFEROUS ALDEHYDE AND/OR ODORIFEROUS KETONE FOR INCREASING AND PROLONGING ODOR INTENSITY HENKEL AG & CO. KGAA (DE) 2017-03-23 WO claimed
WO-2017046282-A1 TRANSPARENT LIQUIDS, IN PARTICULAR FABRIC TREATMENT AGENTS, CONTAINING PERFUME AND MICROCAPSULES WITH AN ODOR MODULATOR COMPOUND HENKEL AG & CO. KGAA (DE) 2017-03-23 WO claimed
US-9557297-B2 Alpha- and chi-diketone reactants for charge transfer reactions in mass spectrometers BRUKER DALTONIK GMBH (DE) 2017-01-31 US claimed
US-20130115711-A1 REACTANTS FOR CHARGE TRANSFER REACTIONS IN MASS SPECTROMETERS BRUKER DALTONIK GMBH (DE) 2013-05-09 US claimed
EP-1284950-A1 PROCESS FOR THE PRODUCTION OF 2,2,6-TRIMETHYLCYCLOHEXANE-1,4-DIONE Degussa AG (DE) 2003-02-26 EP claimed
US-20020165414-A1 Process for the production of 2,2,6-trimethylcyclohexane-1, 4-dione KRILL STEFFEN (DE) 2002-11-07 US claimed
US-6420609-B2 EPOXIDATION OF ISOPHORONE WITH PERCARBOXYLIC ACID DEGUSSA AG (DE) 2002-07-16 US claimed
US-20020010305-A1 Process for the production of 2,2,6-trimethylcyclohexane-1,4-dione DEGUSSA AG (DE) 2002-01-24 US claimed
WO-2001087811-A1 PROCESS FOR THE PRODUCTION OF 2,2,6-TRIMETHYLCYCLOHEXANE-1,4-DIONE DEGUSSA AG (DE) 2001-11-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165414-A1 Process for the production of 2,2,6-trimethylcyclohexane-1, 4-dione HPD, OXER1, DHPS ALDH1A1 869/4885KDM4E 1957/4885GAA 4461/4885
US-10920176-B2 Transparent liquids, in particular fabric treatment agents, comprising perfume and microcapsules with an odor modulator compound NEFM, TRPA1, ALOX5 ALDH1A1 2979/4885KDM4E 3177/4885GAA 3613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.