Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | SOD1 | P00441 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13180039 | 0.84 | RAPGEF4 (0.39) | GPR3TRPV1SERPINE1FFAR4 | |
| SCHEMBL16729557 | 0.84 | NOTUM (0.47) | IDO1GPR3TRPV1SERPINE1TDO2 | |
| SCHEMBL6846413 | 0.84 | ALDH1A1 (0.44) | IDO1GPR3TRPV1TDO2FFAR4 | |
| SCHEMBL12408677 | 0.81 | IDO1 (0.41) | IDO1SERPINE1FFAR4 | |
| SCHEMBL13019323 | 0.80 | IDO1 (0.39) | IDO1CES2SOD1GPR84MAPT | |
| SCHEMBL21513949 | 0.80 | GABRA1 (0.42) | GPR3TRPV1SERPINE1FFAR4KIF11 | |
| SCHEMBL16729381 | 0.80 | PRKCA (0.43) | IDO1TRPV1SERPINE1FFAR4 | |
| SCHEMBL13144931 | 0.80 | ALDH1A1 (0.39) | IDO1GPR3TRPV1TDO2FFAR4 | |
| SCHEMBL22546679 | 0.80 | FFAR4 (0.32) | GPR3TRPV1FFAR4KIF11 | |
| SCHEMBL11683244 | 0.78 | IDO1 (0.38) | IDO1CES2SOD1TRPV1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1489064-B1 | Preparation of fluorinated acetophenones | SALTIGO GMBH (DE) | 2008-04-16 | — | — | EP | disclosed |
| US-7148384-B2 | Preparation of fluorinated acetophenones | BAYER AKTIENGESELLSCHAFT (DE) | 2006-12-12 | — | — | US | disclosed |
| US-20050043559-A1 | Preparation of fluorinated acetophenones | LANXESS DEUTSCHLAND GMBH (DE) | 2005-02-24 | — | — | US | disclosed |
| EP-1489064-A1 | Preparation of fluorinated acetophenones | Bayer Chemicals AG (DE) | 2004-12-22 | — | — | EP | disclosed |
| US-5484932-A | Halogenation processes in advantageous solvents, and novel bistrifluoromethyl-polyfluoroalkoxybenzenes | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-16 | — | — | US | disclosed |
| EP-0567847-A1 | Halogenation process in advantageous solvents | BAYER AG (DE) | 1993-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043559-A1 | Preparation of fluorinated acetophenones | GNPAT, HNF4A, FAH | IDO1 3600/4885CES2 1911/4885SOD1 4291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.