Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601440 | 0.79 | CA1 (0.59) | LMNAALDH1A1TAAR1CYP19A1KDM4E | |
| SCHEMBL4616855 | 0.79 | RAB9A (0.67) | LMNATDP1HRH3ALDH1A1TAAR1 | |
| SCHEMBL3196995 | 0.79 | LMNA (0.59) | LMNATDP1HRH3ALDH1A1TAAR1 | |
| SCHEMBL4602434 | 0.76 | LMNA (0.50) | LMNATDP1HRH3ALOX15RAB9A | |
| SCHEMBL3220191 | 0.76 | LMNA (0.56) | LMNATDP1HRH3ALDH1A1TAAR1 | |
| SCHEMBL10967040 | 0.75 | LMNA (0.55) | LMNATDP1HRH3ALDH1A1TAAR1 | |
| SCHEMBL2593202 | 0.75 | SMN1; SMN2 (0.51) | LMNATDP1ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL5707323 | 0.75 | CYP1A2 (0.60) | LMNATDP1HRH3ALDH1A1TAAR1 | |
| SCHEMBL603914 | 0.74 | CA1 (0.62) | ALDH1A1CYP19A1KDM4E | |
| SCHEMBL14197641 | 0.74 | ALDH1A1 (0.53) | TDP1ALDH1A1CYP19A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |