SCHEMBL460099

SCHEMBL460099

CCCCCc1cnc2ncnn2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
RAB9A P51151 4/20 0.36
MAPT P10636 4/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
NPC1 O15118 2/20 0.36
STAT3 P40763 1/20 0.36
ATM Q13315 1/20 0.36
RARB P10826 1/20 0.35
CASP3 P42574 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 2/20 0.35
GAA P10253 2/20 0.35
KMT2A Q03164 2/20 0.35
HSD17B10 Q99714 2/20 0.35
USP2 O75604 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13510414 0.81 PDE10A (0.38) RAB9AMAPTNPC1STAT3ALDH1A1
SCHEMBL3646931 0.74 GAA (0.39) SMN1; SMN2ATMKDM4EALDH1A1MEN1
SCHEMBL22951213 0.73 PDE10A (0.35) STAT3ALDH1A1GAAPDE10A
SCHEMBL7250893 0.73 L3MBTL1 (0.39) L3MBTL1TDP1RAB9AMAPTSMN1; SMN2
SCHEMBL168138 0.73 GAA (0.36) SMN1; SMN2ATMGAAHTT
SCHEMBL2364454 0.71 L3MBTL1 (0.37) L3MBTL1TDP1RAB9AMAPTSMN1; SMN2
SCHEMBL20045386 0.68 TDP1 (0.43) L3MBTL1TDP1RAB9AMAPTSMN1; SMN2
SCHEMBL10954801 0.68 RAB9A (0.46) RAB9AMAPTSMN1; SMN2NPC1STAT3
SCHEMBL9297200 0.67 PDE10A (0.42) RAB9AMAPTNPC1KDM4EALDH1A1
SCHEMBL23709740 0.67 TDP1 (0.42) L3MBTL1TDP1RAB9AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080293707-A1 Use of Kiralaxyl for Protecting Phytopathogens, and Corresponding Methods and Compositions BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2008-11-27 US claimed
EP-1926370-A2 METHOD FOR PROTECTING PHYTOPATHOGENIC AGENTS BY KIRALAXYL, THE USE THEREOF AND USED SUBSTANCES BASF SE (DE) 2008-06-04 EP claimed
WO-2007031283-A2 METHOD FOR PROTECTING PHYTOPATHOGENIC AGENTS BY KIRALAXYL, THE USE THEREOF AND USED SUBSTANCES BASF SE (DE) 2007-03-22 WO claimed
EP-4385328-A1 ALPHA-HYDROXYKETONES FOR ENHANCING THE ACTIVITY OF ANTIMICROBIAL AGENTS BASF SE (DE) 2024-06-19 EP disclosed
EP-4289273-A1 COMPOSITION COMPRISING AN ANTIMICROBIAL AGENT AND A N-CYCLOHEXYLDIAZENIUMDIOXY SALT BASF SE (DE) 2023-12-13 EP disclosed
WO-2023111297-A1 LACTONES FOR ENHANCING THE ACTIVITY OF ANTIMICROBIAL AGENTS BASF SE (DE) 2023-06-22 WO disclosed
WO-2023111296-A1 COMPOSITION COMPRISING AN ANTIMICROBIAL AGENT AND A CARBOXAMIDE BASF SE (DE) 2023-06-22 WO disclosed
US-10772322-B2 Use of polymer particles containing insecticide in order to improve the soil mobility of insecticides, insecticide formulas, polymer particles containing insecticide, and method for pest control BASF SE (DE) 2020-09-15 US disclosed
US-20180296459-A1 COMPOSITIONS CONTAINING POLYMERIC, IONIC COMPOUNDS COMPRISING IMIDAZOLIUM GROUPS BASF SE (DE) 2018-10-18 US disclosed
EP-3378313-A1 COMPOSITIONS CONTAINING POLYMERIC, IONIC COMPOUNDS COMPRISING IMIDAZOLIUM GROUPS BASF SE (DE) 2018-09-26 EP disclosed
US-10016354-B2 Compositions containing polymeric, ionic compounds comprising imidazolium groups BASF SE (DE) 2018-07-10 US disclosed
WO-2006117162-A2 METHOD FOR IMPREGNATING LIGNOCELLULOSIC MATERIALS WITH EFFECT AGENTS BASF AKTIENGESELLSCHAFT (DE) 2006-11-09 WO disclosed
WO-2006117158-A1 USE OF AQUEOUS WAX DISPERSIONS TO IMPREGNATE LIGNOCELLULOSE MATERIALS BASF AKTIENGESELLSCHAFT (DE) 2006-11-09 WO disclosed
WO-2006117160-A1 METHOD FOR WATERPROOFING LIGNOCELLULOSIC MATERIALS BASF AKTIENGESELLSCHAFT (DE) 2006-11-09 WO disclosed
WO-2006087227-A2 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER BASF AKTIENGESELLSCHAFT (DE) 2006-08-24 WO disclosed
WO-2006084680-A1 POLYMER COMPOSITIONS AND THEIR USE IN THE PRODUCTION OF ACTIVE OR EFFECTIVE INGREDIENT COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2006-08-17 WO disclosed
WO-2006015791-A2 METHOD FOR PRODUCING AQUEOUS ACTIVE SUBSTANCE COMPOSITIONS OF ACTIVE SUBSTANCES THAT ARE HARDLY SOLUBLE IN WATER BASF AKTIENGESELLSCHAFT (DE) 2006-02-16 WO disclosed
WO-2006002984-A1 LIQUID PESTICIDE COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2006-01-12 WO disclosed
WO-2006000592-A1 USE OF ETHER GROUP-CONTAINING POLYMERS AS SOLUBILIZERS BASF AKTIENGESELLSCHAFT (DE) 2006-01-05 WO disclosed
WO-2005121201-A1 AMPHIPHILIC POLYMER COMPOSITIONS AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 2005-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293707-A1 Use of Kiralaxyl for Protecting Phytopathogens, and Corresponding Methods and Compositions PHYKPL, AGL, AGXT L3MBTL1 121/4885TDP1 1523/4885RAB9A 1976/4885
US-20180296459-A1 COMPOSITIONS CONTAINING POLYMERIC, IONIC COMPOUNDS COMPRISING IMIDAZOLIUM GROUPS PUF60, POLR1C, PICALM L3MBTL1 2310/4885TDP1 1127/4885RAB9A 3412/4885
US-10016354-B2 Compositions containing polymeric, ionic compounds comprising imidazolium groups PUF60, POLR1C, PICALM L3MBTL1 2310/4885TDP1 1127/4885RAB9A 3412/4885
US-10772322-B2 Use of polymer particles containing insecticide in order to improve the soil mobility of insecticides, insecticide formulas, polymer particles containing insecticide, and method for pest control PIR, CBR3, GSR L3MBTL1 3438/4885TDP1 2773/4885RAB9A 1901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.