Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601675 | 0.87 | SLC6A5 (0.47) | MAOBSLC6A5PDE4BMAPK1CYP2B6 | |
| SCHEMBL4603982 | 0.82 | TP53 (0.42) | MAOBSLC6A5PDE4BHTTCYP2B6 | |
| SCHEMBL4249982 | 0.78 | TAS1R3 (0.41) | MAOBSLC6A5PDE4BLMNACYP2B6 | |
| SCHEMBL4248762 | 0.77 | CTSK (0.44) | SLC6A5CYP2B6 | |
| SCHEMBL4240867 | 0.76 | P2RX7 (0.43) | SLC6A5L3MBTL1 | |
| SCHEMBL4241529 | 0.75 | SLC6A5 (0.44) | SLC6A5LMNACYP2B6L3MBTL1TDP1 | |
| SCHEMBL4602859 | 0.75 | RIPK1 (0.33) | THRBMAOAMAOBSLC6A5LMNA | |
| SCHEMBL12799708 | 0.74 | MAOB (0.44) | THRATHRBMAOAMAOBPDE4B | |
| SCHEMBL2283999 | 0.73 | LMNA (0.57) | THRATHRBPDE4BLMNAMAPK1 | |
| SCHEMBL3287601 | 0.72 | CYP2B6 (0.41) | THRATHRBPDE4BLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940780-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049728-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |