Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 14/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459381 | 0.86 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL458882 | 0.77 | — | — | |
| SCHEMBL459837 | 0.77 | — | — | |
| SCHEMBL461249 | 0.70 | PIM1 (0.31) | KCNH2 | |
| SCHEMBL461088 | 0.69 | PLAT (0.31) | — | |
| SCHEMBL1679711 | 0.64 | GPR119 (0.57) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL461993 | 0.64 | SLC6A4 (0.37) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL120997 | 0.63 | GPR119 (0.34) | KCNH2 | |
| SCHEMBL470673 | 0.63 | OPRK1 (0.31) | KCNH2 | |
| SCHEMBL461635 | 0.62 | GPR119 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |