Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 4/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461088 | 0.87 | PLAT (0.31) | PLAT | |
| SCHEMBL459381 | 0.83 | SLC6A4 (0.41) | KCNH2 | |
| SCHEMBL460168 | 0.70 | SLC6A4 (0.46) | KCNH2 | |
| SCHEMBL462833 | 0.69 | PLAT (0.34) | PLATCNR2 | |
| SCHEMBL461247 | 0.63 | GPR119 (0.45) | KCNH2CNR2 | |
| SCHEMBL461250 | 0.63 | GPR119 (0.45) | KCNH2CNR2 | |
| SCHEMBL461248 | 0.63 | GPR119 (0.45) | KCNH2CNR2 | |
| SCHEMBL461993 | 0.63 | SLC6A4 (0.37) | KCNH2 | |
| SCHEMBL1679711 | 0.62 | GPR119 (0.57) | KCNH2CNR2 | |
| SCHEMBL461135 | 0.60 | GPR119 (0.61) | KCNH2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |