Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 12/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | GFER | P55789 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226363 | 0.76 | S100B (0.56) | S100BMAPTALDH1A1MAPK1GFER | |
| SCHEMBL10871492 | 0.75 | STS (0.56) | S100BMAPTALDH1A1MAPK1GFER | |
| SCHEMBL28178459 | 0.75 | CYP1A2 (0.45) | MAPTALDH1A1NPSR1L3MBTL1HTT | |
| SCHEMBL29669768 | 0.74 | L3MBTL1 (0.50) | MAPTALDH1A1NPSR1L3MBTL1LMNA | |
| SCHEMBL473085 | 0.74 | L3MBTL1 (0.50) | MAPTALDH1A1NPSR1L3MBTL1LMNA | |
| Acetamide SCHEMBL10826862 | 0.74 | S100B (0.80) | S100BMAPTALDH1A1MAPK1GFER | |
| SCHEMBL9641577 | 0.74 | STS (0.55) | S100BMAPTALDH1A1MAPK1GFER | |
| SCHEMBL12288715 | 0.73 | ACHE (0.51) | S100BMAPTALDH1A1MAPK1GFER | |
| SCHEMBL2191597 | 0.73 | PDE10A (0.45) | MAPTALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9684802 | 0.71 | S100B (0.55) | S100BMAPTALDH1A1MAPK1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | claimed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | claimed |
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |