Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAOK1 | Q7L7X3 | 3/20 | 0.34 |
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 4/20 | 0.33 |
| ▸ | CTSS | P25774 | 4/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.31 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.31 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460186 | 1.00 | TAOK1 (0.34) | TAOK1TAOK3CTSBCTSSCTSK | |
| SCHEMBL405304 | 0.84 | TAOK1 (0.39) | TAOK1TAOK3CTSBCTSSCTSK | |
| SCHEMBL1095466 | 0.83 | TAOK1 (0.37) | TAOK1TAOK3CTSBCTSSCTSK | |
| SCHEMBL1095469 | 0.83 | TAOK1 (0.37) | TAOK1TAOK3CTSBCTSSCTSK | |
| SCHEMBL460187 | 0.77 | TAOK1 (0.33) | TAOK1TAOK3CTSBCTSSCTSK | |
| SCHEMBL5934090 | 0.75 | TAOK1 (0.37) | TAOK1TAOK3CTSBCTSSCTSK | |
| SCHEMBL402861 | 0.73 | DRD2 (0.42) | TAOK1TAOK3LMNAALDH1A1 | |
| SCHEMBL1095582 | 0.72 | TAOK1 (0.42) | TAOK1TAOK3CTSSTAS1R3TAS1R1 | |
| SCHEMBL400722 | 0.72 | CTSS (0.38) | TAOK1TAOK3CTSBCTSSCTSK | |
| SCHEMBL1096052 | 0.71 | KIFC1 (0.41) | TAOK1TAOK3TAS1R3TAS1R1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101640-B2 | Antibacterial agents | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| US-20110172174-A1 | Antibacterial agents | NOVARTIS VACCINES AND DIAGNOSTICS INC. | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172174-A1 | Antibacterial agents | MRPL21, SI, PGLS | TAOK1 1470/4885TAOK3 2857/4885CTSB 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.