Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460187 | 0.76 | TAOK1 (0.33) | TAOK1TAOK3 | |
| SCHEMBL402861 | 0.75 | DRD2 (0.42) | TAOK1TAOK3 | |
| SCHEMBL400722 | 0.71 | CTSS (0.38) | TAOK1TAOK3 | |
| SCHEMBL5934090 | 0.70 | TAOK1 (0.37) | TAOK1TAOK3 | |
| SCHEMBL405304 | 0.70 | TAOK1 (0.39) | TAOK1TAOK3 | |
| SCHEMBL460185 | 0.70 | TAOK1 (0.34) | TAOK1TAOK3 | |
| SCHEMBL460186 | 0.70 | TAOK1 (0.34) | TAOK1TAOK3 | |
| SCHEMBL1095469 | 0.69 | TAOK1 (0.37) | TAOK1TAOK3 | |
| SCHEMBL1095466 | 0.69 | TAOK1 (0.37) | TAOK1TAOK3 | |
| SCHEMBL10286754 | 0.65 | TAOK1 (0.43) | TAOK1TAOK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101640-B2 | Antibacterial agents | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| US-20110172174-A1 | Antibacterial agents | NOVARTIS VACCINES AND DIAGNOSTICS INC. | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172174-A1 | Antibacterial agents | MRPL21, SI, PGLS | TAOK1 1470/4885TAOK3 2857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.