SCHEMBL460306

SCHEMBL460306

CCO[Si](C)(CCCOC(=O)O)OCC

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
ACHE P22303 6/20 0.32
HCAR2 Q8TDS4 3/20 0.32
ATM Q13315 1/20 0.31
NAAA Q02083 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL692978 0.86 ALDH1A1 (0.41) ALDH1A1ACHEATMNAAA
SCHEMBL3341051 0.85 ALDH1A1 (0.52) ALDH1A1ACHE
SCHEMBL28404822 0.83 DGKA (0.41) NAAA
SCHEMBL8839177 0.83 NAAA (0.50) ALDH1A1ACHENAAA
SCHEMBL31348290 0.83 ALOX15 (0.45) ALDH1A1ACHEATM
SCHEMBL4007765 0.82 ALDH1A1 (0.34) ALDH1A1ACHEHCAR2ATMNAAA
SCHEMBL17612292 0.81 ACHE (0.33) ALDH1A1ACHE
Ammonia Solution, Strong SCHEMBL27040886 0.81 ALDH1A1 (0.33) ALDH1A1ACHEHCAR2ATMNAAA
SCHEMBL1809599 0.80 HTR2C (0.39) ALDH1A1NAAA
SCHEMBL15803937 0.80 GAA (0.52) ALDH1A1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2420543-A1 PRIMER COMPOSITION FOR OPTICAL ARTICLES, AND OPTICAL ARTICLE Tokuyama Corporation (JP) 2012-02-22 EP disclosed
US-20120019888-A1 PRIMER COMPOSITION FOR OPTICAL ARTICLES AND OPTICAL ARTICLES TOKUYAMA CORPORATION (JP) 2012-01-26 US disclosed