Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.61 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11304333 | 0.93 | TDP1 (0.62) | CYP1A2CYP2C19ALDH1A1PLOD2PLOD3 | |
| SCHEMBL5092579 | 0.89 | TDP1 (0.77) | CYP1A2CYP2C19ALDH1A1PLOD2PLOD3 | |
| SCHEMBL15524969 | 0.86 | TDP1 (0.77) | CYP2C19ALDH1A1CYP3A4HPGDRAB9A | |
| SCHEMBL30572 | 0.86 | TDP1 (0.77) | CYP2C19ALDH1A1CYP3A4HPGDRAB9A | |
| SCHEMBL28251466 | 0.86 | TDP1 (0.77) | CYP2C19ALDH1A1CYP3A4HPGDRAB9A | |
| SCHEMBL9195700 | 0.84 | ALDH1A1 (0.77) | CYP1A2CYP2C19ALDH1A1PLOD2PLOD3 | |
| Hydrochloric Acid SCHEMBL27556767 | 0.84 | TDP1 (0.74) | CYP2C19ALDH1A1CYP3A4HPGDRAB9A | |
| SCHEMBL1157353 | 0.81 | ALDH1A1 (0.66) | CYP1A2CYP2C19ALDH1A1PLOD2PLOD3 | |
| SCHEMBL7539034 | 0.81 | GPR84 (0.51) | CYP3A4RAB9ANPC1LMNAL3MBTL1 | |
| SCHEMBL3247901 | 0.81 | PLOD2 (0.65) | CYP1A2CYP2C19ALDH1A1PLOD2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287492-A1 | Alkylpyridyl Quinolines as Nk3 Receptor Modulators | ASTRAZENECA AB (SE) | 2008-11-20 | — | — | US | claimed |
| CN-113816899-B | Method for generating ketone or ester by catalytic oxidation of substituted aromatic compound with carbon material | 浙江大学衢州研究院 | 2023-04-14 | — | — | CN | disclosed |
| CN-113816899-A | Method for generating ketone or ester by catalytic oxidation of substituted aromatic compound with carbon material | 浙江大学衢州研究院 | 2021-12-21 | — | — | CN | disclosed |
| US-20080287492-A1 | Alkylpyridyl Quinolines as Nk3 Receptor Modulators | ASTRAZENECA AB (SE) | 2008-11-20 | — | — | US | disclosed |
| US-20080287492-A1 | Alkylpyridyl Quinolines as Nk3 Receptor Modulators | ASTRAZENECA AB (SE) | 2008-11-20 | — | — | US | disclosed |
| US-20080287492-A1 | Alkylpyridyl Quinolines as Nk3 Receptor Modulators | ASTRAZENECA AB (SE) | 2008-11-20 | — | — | US | disclosed |
| EP-1915361-A1 | ALKYLPYRIDYL QUINOLINES AS NK3 RECEPTOR MODULATORS | AstraZeneca AB (SE) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007018466-A1 | ALKYLPYRIDYL QUINOLINES AS NK3 RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | WO | disclosed |
| WO-2007018466-A1 | ALKYLPYRIDYL QUINOLINES AS NK3 RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287492-A1 | Alkylpyridyl Quinolines as Nk3 Receptor Modulators | ADORA3, KCNA3, TACR1 | CYP1A2 756/4885CYP2C19 568/4885ALDH1A1 2243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.