Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.77 |
| ▸ | NPC1 | O15118 | 1/20 | 0.77 |
| ▸ | CASP3 | P42574 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 1/20 | 0.77 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.77 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.77 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.58 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4603533 | 0.89 | CYP1A2 (0.61) | TDP1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL839278 | 0.87 | TDP1 (1.00) | TDP1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL11304333 | 0.82 | TDP1 (0.62) | TDP1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL3070677 | 0.82 | TDP1 (0.89) | TDP1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL9195700 | 0.81 | ALDH1A1 (0.77) | TDP1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL9774493 | 0.81 | NPC1 (0.79) | TDP1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL10269837 | 0.81 | TDP1 (0.79) | TDP1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL8559822 | 0.80 | TDP1 (0.85) | TDP1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL9242650 | 0.80 | TDP1 (0.85) | TDP1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL7426101 | 0.80 | TDP1 (0.85) | TDP1NPC1CASP3RAB9ASENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427632-B2 | Factor Xa inhibitors | ELI LILLY AND COMPANY (US) | 2008-09-23 | — | — | US | disclosed |
| US-20060052606-A1 | Factor xa Inhibitors | ELI LILLY AND COMPANY | 2006-03-09 | — | — | US | disclosed |
| EP-1581493-A1 | FACTOR XA INHIBITORS | ELI LILLY AND COMPANY (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004060872-A1 | FACTOR XA INHIBITORS | ELI LILLY AND COMPANY (US) | 2004-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052606-A1 | Factor xa Inhibitors | F12, F11, SERPINC1 | TDP1 1296/4885NPC1 2053/4885CASP3 849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.