Piperidine

Piperidine

SCHEMBL4603677

C1CCNCC1.NC(=O)Cl

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.53
KDM4E B2RXH2 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39
ATM Q13315 1/20 0.39
CYP2D6 P10635 1/20 0.39
CA2 P00918 1/20 0.37
CHKA P35790 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CXCR4 P61073 1/20 0.37
EPHX1 P07099 1/20 0.33
SLC6A1 P30531 2/20 0.31
TSHR P16473 2/20 0.31
SLC6A11 P48066 1/20 0.31
LMNA P02545 1/20 0.31
SLC6A13 Q9NSD5 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Azepane SCHEMBL9671876 1.00 ALDH1A1 (0.53) ALDH1A1KDM4EKMT2AMAPTATM
Pyrrolidine SCHEMBL3402069 0.97
Piperidine SCHEMBL3283269 0.88 ALDH1A1 (0.60) ALDH1A1KDM4EKMT2AMAPTATM
Piperidine SCHEMBL7344752 0.88 ALDH1A1 (0.60) ALDH1A1KDM4EKMT2AMAPTATM
Piperidine SCHEMBL2675445 0.88 ALDH1A1 (0.60) ALDH1A1KDM4EKMT2AMAPTATM
Azepane SCHEMBL27420992 0.88 ALDH1A1 (0.60) ALDH1A1KDM4EKMT2AMAPTATM
Piperidine SCHEMBL11283067 0.85 ALDH1A1 (0.56) ALDH1A1KDM4EKMT2AMAPTATM
Piperidine SCHEMBL10778074 0.85 ALDH1A1 (0.56) ALDH1A1KDM4EKMT2AMAPTATM
Azepane SCHEMBL11282804 0.85 ALDH1A1 (0.56) ALDH1A1KDM4EKMT2AMAPTATM
Azepane SCHEMBL29776406 0.85 ALDH1A1 (0.56) ALDH1A1KDM4EKMT2AMAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11358928-B2 Method for producing pentamethylene diisocyanate MITSUI CHEMICALS, INC. (JP) 2022-06-14 US disclosed
US-20210380528-A1 METHOD FOR PRODUCING PENTAMETHYLENE DIISOCYANATE MITSUI CHEMICALS, INC. (JP) 2021-12-09 US disclosed
CN-109415307-B Process for producing pentamethylene diisocyanate 三井化学株式会社 2021-06-04 CN disclosed
EP-3533785-A1 PENTAMETHYLENE DIISOCYANATE PRODUCTION METHOD Mitsui Chemicals, Inc. (JP) 2019-09-04 EP disclosed
CN-109415307-A The manufacturing method of pentamethylene diisocyanate 三井化学株式会社 2019-03-01 CN disclosed
EP-2602244-B1 (Meth) Acrylic acid ester, activation energy ray curing composition, and inkjet recording ink RICOH CO LTD (JP) 2017-07-26 EP disclosed
US-9212132-B2 (Meth)acrylic acid ester, activation energy ray curing composition, and inkjet recording ink RICOH COMPANY LTD. (JP) 2015-12-15 US disclosed
EP-2602244-A1 (Meth) Acrylic acid ester, activation energy ray curing composition, and inkjet recording ink Ricoh Company, Ltd. (JP) 2013-06-12 EP disclosed
US-20130144057-A1 (METH)ACRYLIC ACID ESTER, ACTIVATION ENERGY RAY CURING COMPOSITION, AND INKJET RECORDING INK RICOH COMPANY, LTD. (JP) 2013-06-06 US disclosed
US-8188290-B2 Reacting secondary amine, carbon dioxide, triarylsilyl chloride and halogenation agent GLAXO GROUP LIMITED (GB) 2012-05-29 US disclosed
US-4710527-A STERICALLY HINDERED SPIROACETALS OF POLYALKYLPIPERIDIN-4-ONES ICI AMERICAS INC. (US) 1987-12-01 US disclosed
US-4701485-A Malonate-based light stabilizers for plastics ICI AMERICAS INC. (US) 1987-10-20 US disclosed
US-4690963-A POLYALKYL-1,4-DIOXA-8-AZASPIRO(4.5)DECANE-2,3-DICARBOXYLIC ACIDS, ESTERS OR AMIDES; POLYPROPYLENE FILMS ICI AMERICAS INC. (US) 1987-09-01 US disclosed
US-4689360-A SPIRO RING CONTAINING ESTERS ICI AMERICAS INC. (US) 1987-08-25 US disclosed
US-4687800-A POLYALKYL PIPERIDIN-4-YL CONTAINING ACETAL ESTERS AND AMIDES ICI AMERICAS INC. (US) 1987-08-18 US disclosed
EP-0222512-A2 Malonate compounds useful as light stabilizers for plastics CYTEC TECHNOLOGY CORP. (US) 1987-05-20 EP disclosed
EP-0220034-A2 Malonate derivatives useful as light stabilizers for plastics ICI AMERICAS INC. (US) 1987-04-29 EP disclosed
EP-0219331-A2 Tartrate-based compound useful as stabilizers for polymers ICI AMERICAS INC. (US) 1987-04-22 EP disclosed
EP-0219332-A2 Tartrate compounds useful as light stabilizers for plastics ICI AMERICAS INC. (US) 1987-04-22 EP disclosed
EP-0219333-A2 Oligomeric malonates, useful as light stabilizers for plastics ICI AMERICAS INC. (US) 1987-04-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11358928-B2 Method for producing pentamethylene diisocyanate ACR, TMT1A, MTR ALDH1A1 1843/4885KDM4E 3430/4885KMT2A 2299/4885
US-20130144057-A1 (METH)ACRYLIC ACID ESTER, ACTIVATION ENERGY RAY CURING COMPOSITION, AND INKJET RECORDING INK MNAT1, MLLT1, METTL3 ALDH1A1 53/4885KDM4E 123/4885KMT2A 24/4885
US-20210380528-A1 METHOD FOR PRODUCING PENTAMETHYLENE DIISOCYANATE ACR, TMT1A, MTR ALDH1A1 1843/4885KDM4E 3430/4885KMT2A 2299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.