SCHEMBL4603967

SCHEMBL4603967

C#CCOc1c(F)cc(C(=O)N(C)C2C(C)(C)C2(C)C)cc1F

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.34
MAOB P27338 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4603740 0.79 TAS1R3 (0.34) MAOAMAOB
SCHEMBL4602859 0.78 RIPK1 (0.33) MAOAMAOB
SCHEMBL12377620 0.75 MAOB (0.38) MAOAMAOB
SCHEMBL4249761 0.74 P2RX3 (0.36)
SCHEMBL2287267 0.73 NPC1 (0.40) MAOAMAOB
SCHEMBL2288990 0.73 KDM4E (0.43) MAOAMAOB
SCHEMBL2285882 0.72 NPC1 (0.35) MAOAMAOB
SCHEMBL2287363 0.72 NPC1 (0.46) MAOAMAOB
Hydrochloric Acid SCHEMBL4246132 0.72 NPC1 (0.39) MAOAMAOB
SCHEMBL3797358 0.71 TP53 (0.30) MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1940780-A1 AMIDE COMPOUNDS AND THEIR USE SUMITOMO CHEMICAL CO., LTD. (JP) 2008-07-09 EP disclosed
WO-2007049728-A1 AMIDE COMPOUNDS AND THEIR USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-03 WO disclosed