Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3797358 | 0.85 | TP53 (0.30) | MAOAMAOBTP53 | |
| SCHEMBL4603982 | 0.82 | TP53 (0.42) | MAOBTP53SLC6A5 | |
| SCHEMBL4244884 | 0.79 | CTSK (0.40) | TP53SLC6A5CTSLCTSSCTSK | |
| SCHEMBL2289214 | 0.78 | TP53 (0.58) | TP53SLC6A5THRBLMNA | |
| SCHEMBL4603967 | 0.78 | MAOA (0.34) | MAOAMAOB | |
| SCHEMBL4249769 | 0.77 | TP53 (0.43) | TP53SLC6A5CTSLCTSSCTSK | |
| SCHEMBL4604796 | 0.75 | THRA (0.36) | MAOAMAOBSLC6A5THRBLMNA | |
| SCHEMBL4246197 | 0.75 | P2RX3 (0.34) | MAOBTP53SLC6A5SCN9ACTSL | |
| SCHEMBL4603740 | 0.74 | TAS1R3 (0.34) | MAOAMAOB | |
| SCHEMBL4241632 | 0.74 | CTSS (0.42) | TP53SLC6A5CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940780-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049728-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |