Naphthalene

Naphthalene

SCHEMBL460426

Nc1nc(N)nc(N)n1.c1ccc2ccccc2c1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.57
ADORA1 P30542 2/20 0.57
CYP2A6 P11509 1/20 0.57
ALOX12 P18054 1/20 0.57
POLB P06746 1/20 0.57
ADORA3 P0DMS8 1/20 0.57
ADORA2B P29275 1/20 0.57
CYP1A2 P05177 2/20 0.50
SMN1; SMN2 Q16637 4/20 0.48
KDM4E B2RXH2 2/20 0.48
ALOX15 P16050 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
ALDH1A1 P00352 4/20 0.48
HSD17B10 Q99714 4/20 0.48
CYP3A4 P08684 3/20 0.48
CYP1A1 P04798 1/20 0.46
CYP1B1 Q16678 1/20 0.46
DCPS Q96C86 1/20 0.46
HPGD P15428 3/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22409559 0.83 ALOX15 (0.67) ADORA2AADORA1POLBADORA3ADORA2B
Benzene SCHEMBL19253562 0.81 ADORA2A (0.58) ADORA2AADORA1POLBADORA3ADORA2B
Biphenyl SCHEMBL183386 0.80 ADORA2A (0.75) ADORA2AADORA1POLBADORA3ADORA2B
Acridine SCHEMBL22168564 0.78 ALDH1A1 (0.75) ADORA2AADORA1POLBADORA3ADORA2B
Naphthalene SCHEMBL3058088 0.76 CYP2A6 (0.80) CYP2A6ALOX12CYP1A2SMN1; SMN2ALOX15
SCHEMBL9583239 0.76 CASP1 (0.50) ADORA2AADORA1POLBADORA3ADORA2B
Naphthalene SCHEMBL1332240 0.76 CYP2A6 (1.00) CYP2A6ALOX12CYP1A2L3MBTL1ALDH1A1
SCHEMBL175612 0.76 CASP1 (0.50) ADORA2AADORA1POLBADORA3ADORA2B
Naphthalene SCHEMBL8953 0.76 CYP2A6 (1.00) CYP2A6ALOX12CYP1A2L3MBTL1ALDH1A1
SCHEMBL8465809 0.76 CASP1 (0.50) ADORA2AADORA1POLBADORA3ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9284225-B2 Composite concrete for floor slabs and rafts PRIMEKSS RABINE NORTH AMERICA LLC (US) 2016-03-15 US claimed
EP-2493834-A2 COMPOSITE CONCRETE FOR FLOOR SLABS AND RAFTS Primeteh A/s (LV) 2012-09-05 EP claimed
US-20120021206-A1 COMPOSITE CONCRETE FOR FLOOR SLABS AND RAFTS PRIMETEH, A/S (LV) 2012-01-26 US claimed
WO-2011053103-A2 COMPOSITE CONCRETE FOR FLOOR SLABS AND RAFTS PRIMETEH, A/S (LV) 2011-05-05 WO claimed
US-9284225-B2 Composite concrete for floor slabs and rafts PRIMEKSS RABINE NORTH AMERICA LLC (US) 2016-03-15 US disclosed
EP-2493834-A2 COMPOSITE CONCRETE FOR FLOOR SLABS AND RAFTS Primeteh A/s (LV) 2012-09-05 EP disclosed
US-20120021206-A1 COMPOSITE CONCRETE FOR FLOOR SLABS AND RAFTS PRIMETEH, A/S (LV) 2012-01-26 US disclosed
WO-2011053103-A2 COMPOSITE CONCRETE FOR FLOOR SLABS AND RAFTS PRIMETEH, A/S (LV) 2011-05-05 WO disclosed