Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 9/20 | 0.39 |
| ▸ | CNR1 | P21554 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602808 | 0.96 | HPGD (0.44) | ALDH1A1PTK2CNR2CNR1HPGD | |
| SCHEMBL4605222 | 0.96 | HPGD (0.41) | HTR2AALDH1A1CNR2CNR1HPGD | |
| SCHEMBL4604638 | 0.95 | ALDH1A1 (0.46) | ALDH1A1CNR2CNR1HPGD | |
| SCHEMBL4603249 | 0.88 | HTR2A (0.41) | TAS1R3TAS1R1TAS1R2HTR2AALDH1A1 | |
| SCHEMBL4602234 | 0.83 | KDM4E (0.45) | TAS1R3TAS1R1TAS1R2ALDH1A1POLB | |
| SCHEMBL4603506 | 0.83 | HPGD (0.45) | HTR2AALDH1A1CNR2CNR1MEN1 | |
| SCHEMBL4602587 | 0.83 | HPGD (0.42) | HTR2AALDH1A1POLBCNR2CNR1 | |
| SCHEMBL4604443 | 0.83 | TAS1R3 (0.50) | TAS1R3TAS1R1TAS1R2CNR2CNR1 | |
| SCHEMBL4603541 | 0.80 | ALDH1A1 (0.48) | ALDH1A1POLBPTK2CNR2CNR1 | |
| SCHEMBL4603116 | 0.78 | ALDH1A1 (0.42) | TAS1R3TAS1R1TAS1R2HTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940780-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049728-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |