Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634051 | 0.90 | KDM4E (0.36) | EPHX2ALDH1A1 | |
| SCHEMBL4600596 | 0.79 | CHRNB2 (0.31) | — | |
| SCHEMBL21594121 | 0.74 | — | — | |
| SCHEMBL239490 | 0.68 | ALDH1A1 (0.45) | EPHX2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1965268 | 0.66 | ALDH1A1 (0.43) | EPHX2ALDH1A1 | |
| SCHEMBL4602173 | 0.66 | ANPEP (0.31) | — | |
| SCHEMBL7054611 | 0.65 | — | — | |
| SCHEMBL12154382 | 0.64 | GNAI3 (0.56) | EPHX2ALDH1A1 | |
| SCHEMBL10962985 | 0.64 | KDM4E (0.47) | EPHX2ALDH1A1 | |
| SCHEMBL1505133 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124085-A2 | METHODS OF USING COMBINATIONS OF MEK AND JAK-2 INHIBITORS | EXELIXIS, INC. (US) | 2008-10-16 | — | — | WO | disclosed |