Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | COMT | P21964 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46119 | 0.89 | — | — | |
| SCHEMBL46114 | 0.88 | MEN1 (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL46375 | 0.87 | NPSR1 (0.31) | ALDH1A1MEN1KMT2A | |
| SCHEMBL12071745 | 0.86 | EZH2 (0.32) | ALDH1A1MEN1KMT2A | |
| SCHEMBL46140 | 0.85 | TSHR (0.32) | SIGMAR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL46054 | 0.83 | L3MBTL1 (0.30) | L3MBTL1 | |
| SCHEMBL46060 | 0.83 | OPRM1 (0.39) | SIGMAR1OPRK1THRBKCNH2CCR5 | |
| SCHEMBL15032118 | 0.82 | L3MBTL1 (0.40) | SIGMAR1ALDH1A1MAPTL3MBTL1KCNH2 | |
| SCHEMBL12071753 | 0.82 | P2RX7 (0.39) | ALDH1A1L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL12071744 | 0.81 | P2RX7 (0.36) | SIGMAR1ALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151249-A2 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2010066780-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-17 | — | — | WO | disclosed |