Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46119 | 0.91 | — | — | |
| SCHEMBL12071744 | 0.87 | P2RX7 (0.36) | TSHRKMT2AMEN1SIGMAR1NPC1 | |
| SCHEMBL46053 | 0.85 | SIGMAR1 (0.32) | KMT2AMEN1SIGMAR1ALDH1A1MAPT | |
| SCHEMBL46141 | 0.85 | OPRM1 (0.34) | TSHRKMT2AMEN1SIGMAR1RAB9A | |
| SCHEMBL15032124 | 0.84 | L3MBTL1 (0.39) | SIGMAR1 | |
| SCHEMBL46375 | 0.84 | NPSR1 (0.31) | TSHRKMT2AMEN1NPC1RAB9A | |
| SCHEMBL12071753 | 0.84 | P2RX7 (0.39) | TSHRKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL46054 | 0.83 | L3MBTL1 (0.30) | — | |
| SCHEMBL46100 | 0.83 | EPHX2 (0.34) | KMT2AMEN1SIGMAR1POLBALDH1A1 | |
| SCHEMBL46353 | 0.81 | LMNA (0.32) | SIGMAR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151249-A2 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2010066780-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-17 | — | — | WO | disclosed |