Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30545241 | 1.00 | GNPAT (0.53) | GNPATCA2MAPK1NOD1CA1 | |
| SCHEMBL16948271 | 0.94 | GNPAT (0.51) | GNPATNOD1SLC1A2SLC1A1GPR84 | |
| SCHEMBL28754574 | 0.92 | GPR84 (0.53) | GNPATNOD1SLC1A2SLC1A1GPR84 | |
| SCHEMBL27398886 | 0.86 | — | — | |
| SCHEMBL6238817 | 0.82 | CA2 (0.52) | CA2MAPK1NOD1CA1SLC1A3 | |
| SCHEMBL429475 | 0.80 | CA2 (0.50) | CA2MAPK1NOD1CA1SLC1A3 | |
| SCHEMBL197378 | 0.80 | NOD1 (0.53) | CA2MAPK1NOD1CA1SLC1A3 | |
| SCHEMBL198715 | 0.80 | NOD1 (0.53) | CA2MAPK1NOD1CA1SLC1A3 | |
| SCHEMBL197377 | 0.80 | NOD1 (0.53) | CA2MAPK1NOD1CA1SLC1A3 | |
| SCHEMBL288045 | 0.80 | CA2 (0.50) | CA2MAPK1NOD1CA1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404362-B1 | SIGNAL-1/SIGNAL-2 BIFUNCTIONAL PEPTIDE INHIBITORS | UNIV KANSAS (US) | 2008-07-09 | — | — | EP | disclosed |