Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460531 | 0.72 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2GAAMAPK1KDM4E | |
| SCHEMBL425854 | 0.67 | KMT2A (0.40) | ALDH1A1SMN1; SMN2HPGDALOX15MAPK1 | |
| SCHEMBL461872 | 0.63 | OPRM1 (0.40) | ALDH1A1HPGDHTTMEN1KMT2A | |
| SCHEMBL2743353 | 0.61 | CNR1 (0.49) | ALDH1A1SMN1; SMN2HPGDHTTKDM4E | |
| SCHEMBL13696876 | 0.59 | CLK4 (0.53) | ALDH1A1SMN1; SMN2HPGDKDM4EMEN1 | |
| SCHEMBL22173634 | 0.58 | CHRNA7 (0.46) | GAAMAPK1KDM4EMAPTPTGS2 | |
| SCHEMBL425575 | 0.57 | BCHE (0.56) | ALDH1A1SMN1; SMN2GAAHPGDKDM4E | |
| SCHEMBL6736048 | 0.56 | PIK3CA (0.66) | PIK3CAALDH1A1SMN1; SMN2GAAHPGD | |
| SCHEMBL22897599 | 0.55 | MAPT (0.42) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL11604408 | 0.55 | L3MBTL1 (0.51) | ALDH1A1SMN1; SMN2GAAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | FAAH, FAAH2, ASAH1 | PIK3CA 1962/4885ALDH1A1 294/4885SMN1; SMN2 2818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.