SCHEMBL4607420

SCHEMBL4607420

FC(F)(F)Cc1cccc(-c2cc(Cl)[c]cc2I)c1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4607416 0.80
SCHEMBL533642 0.69 AGXT (0.41)
SCHEMBL10451551 0.66 PNMT (0.54)
SCHEMBL23140929 0.66 IDO1 (0.48)
SCHEMBL21507826 0.66 SHMT1 (0.36)
SCHEMBL4608811 0.65 METAP2 (0.33)
SCHEMBL193422 0.65
Formamide SCHEMBL6016424 0.64 AGXT (0.45)
SCHEMBL4606815 0.63 RORB (0.43)
SCHEMBL4431948 0.62 MEN1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1948649-A2 FUNGICIDAL CARBOXAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-30 EP disclosed
WO-2007014290-A2 FUNGICIDAL CARBOXAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-02-01 WO disclosed