Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5378515 | 1.00 | NUDT1 (0.37) | NUDT1PIK3C3DPP4 | |
| SCHEMBL7654045 | 1.00 | NUDT1 (0.37) | NUDT1PIK3C3DPP4 | |
| SCHEMBL24784976 | 0.78 | NUDT1 (0.37) | NUDT1PIK3C3 | |
| SCHEMBL19275760 | 0.78 | NUDT1 (0.37) | NUDT1PIK3C3 | |
| SCHEMBL24621749 | 0.74 | NUDT1 (0.35) | NUDT1PIK3C3 | |
| SCHEMBL19275751 | 0.74 | NUDT1 (0.35) | NUDT1PIK3C3 | |
| SCHEMBL5078738 | 0.74 | DPP4 (0.38) | NUDT1PIK3C3DPP4 | |
| SCHEMBL17386672 | 0.71 | LMNA (0.40) | NUDT1PIK3C3DPP4 | |
| SCHEMBL14624925 | 0.67 | — | — | |
| SCHEMBL6113839 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3853219-B1 | HERBICIDALLY ACTIVE SUBSTITUTED PHENYLPYRIMIDINE HYDRAZIDES | BAYER AG (DE) | 2023-07-12 | — | — | EP | disclosed |
| US-20220033363-A1 | HERBICIDALLY ACTIVE SUBSTITUTED PHENYLPYRIMIDINE HYDRAZIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2022-02-03 | — | — | US | disclosed |
| WO-2020058062-A1 | HERBICIDALLY ACTIVE SUBSTITUTED PHENYLPYRIMIDINE HYDRAZIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-03-26 | — | — | WO | disclosed |
| US-8207156-B2 | Substituted pyrazoline compounds, their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2012-06-26 | — | — | US | disclosed |
| EP-1946777-A1 | Substituted pyrazoline for preventing weight gain | Laboratorios del Dr. Esteve S.A. (ES) | 2008-07-23 | — | — | EP | disclosed |
| EP-1946778-A1 | Active substance combination for the treatment of diabetes | Laboratorios del Dr. Esteve S.A. (ES) | 2008-07-23 | — | — | EP | disclosed |
| US-20070185086-A1 | Pharmaceutical Compositions and Methods for Effecting Dopamine Release | BENCHERIF MEROUANE | 2007-08-09 | — | — | US | disclosed |
| US-7214686-B2 | Pharmaceutical compositions and methods for effecting dopamine release | TARGACEPT, INC. (US) | 2007-05-08 | — | — | US | disclosed |
| US-20070021398-A1 | Substituted Pyrazoline Compounds, their Preparation and Use as Medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-01-25 | — | — | US | disclosed |
| EP-1743888-A1 | Carbonyl substituted pyrazoline compounds, their preparation and use as CB1 receptor modulators | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-01-17 | — | — | EP | disclosed |
| EP-1066287-B1 | AZATRICYCLIC COMPOUNDS | TARGACEPT INC (US) | 2003-09-03 | — | — | EP | disclosed |
| EP-1068208-B1 | AZATRICYCLO[3.3.1.1] DECANE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | TARGACEPT INC (US) | 2003-05-14 | — | — | EP | disclosed |
| US-6525065-B1 | Central nervous system disorders; administering an endo or exo form of a 1-aza-2-(3-pyridyl)bicyclo(2.2.1)heptane, or a 1-aza-7-(3-pyridyl)bicyclo(3.2.2) nonane, or a 1-aza-2-(3-pyridyl)bicyclo(2.2.2)octane | TARGACEPT, INC. | 2003-02-25 | — | — | US | disclosed |
| US-6417359-B1 | 1-AZAADAMANTANE DERIVATIVES; NICOTINIC CHOLINERGIC RECEPTOR DRUGS; NEUROPROTECTIVE AGENTS; NERVOUS SYSTEM, PSYCHOLOGICAL, AND GLANDULAR DISORDERS; SIDE EFFECT REDUCTION | TARGACEPT, INC. | 2002-07-09 | — | — | US | disclosed |
| US-6407103-B2 | POTENT ENZYME INHIBITORS OF CYCLIN-DEPENDENT KINASES RELATING TO THE CATALYTIC SUBUNITS CDK1-9 AND THEIR REGULATORY SUBUNITS CYCLINS A-H; ANTIPROLIFERATIVE, -CARCINOGENIC AND -TUMOR AGENTS; VIRICIDES; MODULATORS OF DNA/RNA BIOSYNTHESIS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-06-18 | — | — | US | disclosed |
| US-20010027195-A1 | Indeno [1,2-c]pyrazol-4-ones and their uses | DUPONT PHARMACEUTICALS COMPANY | 2001-10-04 | — | — | US | disclosed |
| US-6211372-B1 | THERAPY FOR NERVOUS SYSTEM DISORDERS | CROOKS PETER ANTHONY (US) | 2001-04-03 | — | — | US | disclosed |
| US-6057446-A | Certain 1-aza-tricyclo [3.3.1-13,7 ] decane compounds | TARGACEPT, INC., A CORPORATION OF DELAWARE | 2000-05-02 | — | — | US | disclosed |
| US-5986100-A | 1-AZA-2-(3-PYRIDYL)-1-AZATRICYCLO(3.3.1.1 3,7)DECANE NICOTINIC CHOLINERGIC AGENTS | TARGACEPT, INC. | 1999-11-16 | — | — | US | disclosed |
| US-5952339-A | Pharmaceutical compositions and methods of using nicotinic antagonists for treating a condition or disorder characterized by alteration in normal neurotransmitter release | TARGACEPT, INC. | 1999-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010027195-A1 | Indeno [1,2-c]pyrazol-4-ones and their uses | CDK1, CCNA1, CDK19 | NUDT1 2399/4885PIK3C3 1504/4885DPP4 3986/4885 |
| US-20070185086-A1 | Pharmaceutical Compositions and Methods for Effecting Dopamine Release | COMT, SLC6A3, HTR2A | NUDT1 281/4885PIK3C3 1502/4885DPP4 2531/4885 |
| US-20220033363-A1 | HERBICIDALLY ACTIVE SUBSTITUTED PHENYLPYRIMIDINE HYDRAZIDES | DDT, CBR3, CAT | NUDT1 377/4885PIK3C3 1191/4885DPP4 31/4885 |
| US-20070021398-A1 | Substituted Pyrazoline Compounds, their Preparation and Use as Medicaments | PIR, SYMPK, P2RX5 | NUDT1 158/4885PIK3C3 488/4885DPP4 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.