Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608059 | 0.84 | NAMPT (0.36) | SIGMAR1ALDH1A1HPGD | |
| SCHEMBL3813465 | 0.81 | HDAC1 (0.46) | HDAC2HDAC8HDAC6SMN1; SMN2ALDH1A1 | |
| SCHEMBL3811254 | 0.75 | ALDH1A1 (0.36) | L3MBTL3SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3812022 | 0.74 | HDAC1 (0.46) | HDAC6ALDH1A1HPGDTSHR | |
| SCHEMBL12576932 | 0.74 | HRH3 (0.37) | HDAC8HDAC6SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3814369 | 0.73 | HRH3 (0.39) | L3MBTL3SIGMAR1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5499445 | 0.72 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL3811818 | 0.72 | AOC3 (0.40) | L3MBTL1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3811439 | 0.72 | LMNA (0.37) | ALDH1A1HPGD | |
| SCHEMBL3811384 | 0.71 | CCR5 (0.40) | SMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948190-A2 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | TRANSTECH PHARMA (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007051810-A2 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | TRANSTECH PHARMA (US) | 2007-05-10 | — | — | WO | disclosed |