Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3813465 | 0.85 | HDAC1 (0.46) | ALDH1A1HTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL4608058 | 0.84 | HDAC2 (0.36) | ALDH1A1HPGDSIGMAR1 | |
| SCHEMBL3811254 | 0.79 | ALDH1A1 (0.36) | ALDH1A1HPGDGAACA2 | |
| SCHEMBL3812022 | 0.78 | HDAC1 (0.46) | ALDH1A1HPGDGAA | |
| SCHEMBL12576932 | 0.78 | HRH3 (0.37) | ALDH1A1HPGDGAACA2 | |
| SCHEMBL3814369 | 0.77 | HRH3 (0.39) | ALDH1A1HPGDGAASIGMAR1GLA | |
| SCHEMBL3811439 | 0.75 | LMNA (0.37) | ALDH1A1HPGD | |
| SCHEMBL3811818 | 0.75 | AOC3 (0.40) | ALDH1A1HPGDMAPT | |
| SCHEMBL3811384 | 0.75 | CCR5 (0.40) | ALDH1A1 | |
| SCHEMBL12640409 | 0.75 | CA2 (0.38) | ALDH1A1HPGDHSD11B1CA2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101351209-A | Pharmaceutical use of substituted amides | TRANSTECH PHARMA INC (US) | 2009-01-21 | — | — | CN | claimed |
| CN-101351209-A | Pharmaceutical use of substituted amides | TRANSTECH PHARMA INC (US) | 2009-01-21 | — | — | CN | disclosed |
| EP-1948190-A2 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | TRANSTECH PHARMA (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007051810-A2 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | TRANSTECH PHARMA (US) | 2007-05-10 | — | — | WO | disclosed |