Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.43 |
| ▸ | KDM1A | O60341 | 4/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608402 | 0.78 | ALDH1A1 (0.38) | MAOBKDM1AALDH1A1BACE1L3MBTL1 | |
| SCHEMBL4608166 | 0.78 | SLC6A2 (0.42) | MAOBTAAR1CYP1A2KDM4EALDH1A1 | |
| SCHEMBL4606554 | 0.78 | KDM1A (0.66) | MAOBKDM1ATAAR1CYP1A2CYP2A6 | |
| SCHEMBL4607809 | 0.77 | GRIA4 (0.44) | MAOBKDM1AALDH1A1 | |
| SCHEMBL4608247 | 0.75 | KDM1A (0.39) | MAOBKDM1ATAAR1CYP1A2CYP2A6 | |
| SCHEMBL3948975 | 0.73 | BACE1 (0.49) | TAAR1CYP1A2CYP2A6KDM4EALDH1A1 | |
| SCHEMBL4607109 | 0.72 | KDM1A (0.43) | MAOBKDM1A | |
| SCHEMBL4604973 | 0.72 | KDM1A (0.61) | MAOBKDM1A | |
| SCHEMBL4607730 | 0.72 | KDM1A (0.49) | MAOBKDM1A | |
| SCHEMBL6532602 | 0.72 | MAOB (0.73) | MAOBTAAR1CYP1A2CYP2A6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | claimed |
| US-6639107-B1 | Potentiating glutamate receptor function | ELI LILLY AND COMPANY | 2003-10-28 | — | — | US | claimed |
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | disclosed |
| US-6639107-B1 | Potentiating glutamate receptor function | ELI LILLY AND COMPANY | 2003-10-28 | — | — | US | disclosed |
| EP-1246797-A1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001042203-A1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-06-14 | — | — | WO | disclosed |