Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 5/20 | 0.34 |
| ▸ | EHMT1 | Q9H9B1 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608155 | 0.80 | EHMT2 (0.37) | ALDH1A1EHMT2EHMT1NMT1GAA | |
| SCHEMBL4609792 | 0.73 | MAPT (0.37) | ALDH1A1MAPTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL13743275 | 0.73 | KMT2A (0.40) | ALDH1A1MAPTEHMT2KMT2ASMN1; SMN2 | |
| SCHEMBL3572453 | 0.67 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2ALMNAPOLB | |
| SCHEMBL24074322 | 0.66 | JAK2 (0.46) | ALDH1A1POLBSMN1; SMN2GAAHTR2A | |
| SCHEMBL322079 | 0.64 | KCNQ3 (0.50) | ALDH1A1MAPTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL9121830 | 0.63 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2ALMNAPOLB | |
| SCHEMBL6640396 | 0.63 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2ALMNAPOLB | |
| SCHEMBL3978834 | 0.62 | NOS3 (0.35) | ALDH1A1MAPTKMT2ALMNAPOLB | |
| SCHEMBL27785371 | 0.62 | KMT2A (0.43) | ALDH1A1MAPTKMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261918-A1 | Silicon Compounds and Their Use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-10-23 | — | — | US | disclosed |
| EP-1824863-B1 | SILICON COMPOUNDS AND THEIR USE | TAKEDA CAMBRIDGE LTD (GB) | 2008-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261918-A1 | Silicon Compounds and Their Use | SOST, SIK2, SCLY | ALDH1A1 2254/4885MAPT 1574/4885EHMT2 1575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.