Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PYGL | P06737 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586238 | 1.00 | NAAA (0.58) | NAAAALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL6384132 | 0.99 | NAAA (0.56) | NAAAALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL29022047 | 0.85 | ALOX5 (0.50) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL8670657 | 0.85 | CA2 (0.54) | NAAAALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL21579700 | 0.85 | CA2 (0.54) | NAAAALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL13892898 | 0.84 | NAAA (0.61) | NAAAALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL12300831 | 0.84 | NAAA (0.60) | NAAAPYGLCA2FOLH1CYP2C9 | |
| SCHEMBL7759090 | 0.83 | CA2 (0.61) | NAAAALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL29036089 | 0.83 | CA2 (0.61) | NAAAALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL5803352 | 0.83 | KDM4E (0.66) | NAAAALDH1A1KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149066-B1 | METHOD OF PREPARING ALKYLATED SALICYLAMIDES | EMISPHERE TECH INC (US) | 2005-11-09 | — | — | EP | claimed |
| EP-3256114-A1 | TREATMENT OF OSTEOPOROSIS | Entera Bio Ltd. (IL) | 2017-12-20 | — | — | EP | disclosed |
| US-20170165369-A1 | METHOD OF TREATING CANCER | INTENSITY THERAPEUTICS, INC. | 2017-06-15 | — | — | US | disclosed |
| WO-2016128973-A1 | TREATMENT OF OSTEOPOROSIS | ENTERA BIO LTD. (IL) | 2016-08-18 | — | — | WO | disclosed |
| CN-102369018-B | Treatment of diabetes and metabolic syndrome | 关键生物科学有限公司 | 2016-08-03 | — | — | CN | disclosed |
| EP-1945243-A1 | USE OF CALCITONIN FOR THE TREATMENT OF RA | Novartis AG (CH) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007051641-A1 | USE OF CALCITONIN FOR THE TREATMENT OF RA | NOVARTIS AG (CH) | 2007-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170165369-A1 | METHOD OF TREATING CANCER | PBK, GZMB, NPC1L1 | NAAA 1268/4885ALDH1A1 3990/4885KDM4E 1887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.