SCHEMBL8670657

SCHEMBL8670657

CCCCC(NC(=O)c1cccc(O)c1O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.54
FNTA P49354 1/20 0.54
FNTB P49356 1/20 0.54
PYGL P06737 2/20 0.47
CYP2C9 P11712 1/20 0.47
ALOX5 P09917 4/20 0.47
MME P08473 1/20 0.46
TAS1R3 Q7RTX0 1/20 0.45
TAS1R1 Q7RTX1 1/20 0.45
LMNA P02545 3/20 0.45
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
HPGD P15428 2/20 0.45
HSD17B10 Q99714 2/20 0.45
TSHR P16473 1/20 0.45
FOLH1 Q04609 2/20 0.44
MET P08581 1/20 0.43
TERT O14746 1/20 0.43
NAAA Q02083 1/20 0.43
AGTR1 P30556 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21579700 1.00 CA2 (0.54) CA2FNTAFNTBPYGLCYP2C9
SCHEMBL21579768 0.92 TAS1R3 (0.50) CA2FNTAFNTBPYGLCYP2C9
SCHEMBL18196692 0.91 FNTA (0.49) CA2FNTAFNTBPYGLCYP2C9
SCHEMBL8524879 0.86 ALOX5 (0.47) CA2FNTAFNTBALOX5KDM4E
SCHEMBL8487903 0.86 ALOX5 (0.47) CA2FNTAFNTBALOX5KDM4E
SCHEMBL6384132 0.86 NAAA (0.56) CA2FNTAFNTBPYGLCYP2C9
SCHEMBL7668122 0.85 ALOX5 (0.64) ALOX5ALDH1A1HPGDHSD17B10TSHR
SCHEMBL4608702 0.85 NAAA (0.58) CA2FNTAFNTBPYGLCYP2C9
SCHEMBL4586238 0.85 NAAA (0.58) CA2FNTAFNTBPYGLCYP2C9
SCHEMBL8489024 0.85 ALOX5 (0.49) CA2ALOX5FOLH1TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5854250-A N-benzoylamino acid derivatives, pharmaceutical compositions containing them and process of preparing same GYOGYSZERKUTATO INTEZET KFT (HU) 1998-12-29 US disclosed
US-5705529-A ANTIISCHEMIC AGENTS, ANTIINFLAMMATORY AGENTS, AGING RESISTANCE, ATHERIOSCLEROSIS, NERVOUS SYSTEM DISORDERS GYOGYSZERKUTATO INTEZET KFT (HK) 1998-01-06 US disclosed
EP-0576941-B1 N-benzoylamino acid derivatives, pharmaceutical compositions containing them and process for preparing same NISSHIN FLOUR MILLING CO (JP) 1997-09-03 EP disclosed
EP-0576941-A1 N-benzoylamino acid derivatives, pharmaceutical compositions containing them and process for preparing same NISSHIN FLOUR MILLING CO., LTD. (JP) 1994-01-05 EP disclosed