Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | GALR1 | P47211 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5137942 | 0.86 | METAP2 (0.33) | METAP2PDE4ACHRNB4CHRNA3 | |
| SCHEMBL4284888 | 0.79 | HSD17B1 (0.45) | — | |
| SCHEMBL6265992 | 0.75 | DYRK1A (0.47) | PDE4A | |
| SCHEMBL4608811 | 0.74 | METAP2 (0.33) | METAP2PDE4ACHRNB4CHRNA3 | |
| SCHEMBL5085424 | 0.71 | METAP2 (0.34) | METAP2PDE4ACHRNB4CHRNA3GALR1 | |
| SCHEMBL10755559 | 0.71 | TSHR (0.42) | — | |
| SCHEMBL5137943 | 0.71 | METAP2 (0.32) | METAP2CHRNB4CHRNA3 | |
| SCHEMBL24730216 | 0.70 | ALOX5 (0.52) | METAP2 | |
| SCHEMBL27925958 | 0.69 | CYP2A6 (0.58) | METAP2CHRNB4CHRNA3 | |
| SCHEMBL11615995 | 0.69 | FGFR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |