Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538268 | 0.71 | ABCB11 (0.60) | DPP4OPRM1OPRK1CACNA2D1CACNA1B | |
| SCHEMBL31495 | 0.71 | ABCB11 (0.60) | DPP4OPRM1OPRK1CACNA2D1CACNA1B | |
| Hydrochloric Acid SCHEMBL4811226 | 0.67 | KEAP1 (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2558458 | 0.67 | ACP3 (0.41) | OPRL1OPRM1OPRK1OPRD1KDM4E | |
| SCHEMBL7727749 | 0.67 | ACP3 (0.41) | KDM4EALDH1A1MAPTCNR1 | |
| SCHEMBL14968308 | 0.66 | ESR1 (0.45) | ALDH1A1SMN1; SMN2CNR1 | |
| SCHEMBL7987419 | 0.65 | TSHR (0.42) | KDM4EALDH1A1MAPTCNR1 | |
| SCHEMBL7019221 | 0.65 | CNR1 (0.47) | DPP4KDM4EALDH1A1MAPTHTT | |
| SCHEMBL7028611 | 0.65 | TDP1 (0.42) | KDM4EALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL11484148 | 0.65 | ACP3 (0.37) | KDM4EALDH1A1MAPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |