Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506736 | 0.83 | PNMT (0.48) | TSHRHIF1ATDP1LMNACYP2C19 | |
| SCHEMBL6601468 | 0.79 | ALDH1A1 (0.39) | TSHRHIF1ATDP1LMNACYP2C19 | |
| SCHEMBL2558458 | 0.79 | ACP3 (0.41) | TSHRHIF1ATDP1LMNACYP2C19 | |
| SCHEMBL7727749 | 0.79 | ACP3 (0.41) | TSHRHIF1ATDP1LMNACYP2C19 | |
| SCHEMBL38142 | 0.76 | ACP3 (0.39) | TSHRHIF1ATDP1LMNACYP2C19 | |
| SCHEMBL7038606 | 0.76 | ADRB2 (0.42) | TSHRHIF1ATDP1LMNACYP2C19 | |
| SCHEMBL22445608 | 0.76 | ACP3 (0.39) | TSHRHIF1ATDP1LMNACYP2C19 | |
| SCHEMBL4840134 | 0.76 | ACP3 (0.43) | TSHRHIF1ATDP1LMNACYP2C19 | |
| SCHEMBL25241487 | 0.76 | GABRA1 (0.46) | TSHRHIF1ATDP1LMNAKDM4E | |
| SCHEMBL5011270 | 0.76 | CES2 (0.40) | CYP2C9CYP3A4MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961266-B2 | Chemoselective methylene hydroxylation in aromatic molecules | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-03-30 | — | — | US | disclosed |
| US-20200087331-A1 | CHEMOSELECTIVE METHYLENE HYDROXYLATION IN AROMATIC MOLECULES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2020-03-19 | — | — | US | disclosed |
| EP-1980563-A1 | Procedure for the preparation of methyl (+)-(S)-Alpha-(O-chlorophenyl)-6,7-dihydrothieno-[3,2-C]pyridine-5(4H) acetate | BATTULA, Srinivasa Reddy (IN) | 2008-10-15 | — | — | EP | disclosed |
| US-6255326-B1 | ANTIINFLAMMATORY AGENT; AUTOIMMUNE DISEASES | AVENTIS PHARMA LIMITED (GB) | 2001-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961266-B2 | Chemoselective methylene hydroxylation in aromatic molecules | PAH, DBH, AHR | TSHR 2351/4885HIF1A 422/4885TDP1 4313/4885 |
| US-20200087331-A1 | CHEMOSELECTIVE METHYLENE HYDROXYLATION IN AROMATIC MOLECULES | PAH, DBH, AHR | TSHR 2351/4885HIF1A 422/4885TDP1 4313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.