SCHEMBL4610229

SCHEMBL4610229

CC(C)(C)C(=O)Nc1ccccc1Cc1ccc(O)cc1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.52
CETP P11597 1/20 0.49
KEAP1 Q14145 1/20 0.47
TSHR P16473 2/20 0.41
MEN1 O00255 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 2/20 0.41
MAOB P27338 1/20 0.41
LMNA P02545 2/20 0.40
HTT P42858 1/20 0.40
KDM4E B2RXH2 1/20 0.40
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1274654 0.89 L3MBTL1 (0.65) L3MBTL1CETPMEN1RAB9AKMT2A
SCHEMBL6096285 0.83 L3MBTL1 (0.56) L3MBTL1KEAP1TSHRMEN1RAB9A
SCHEMBL3774635 0.79 CETP (0.59) L3MBTL1CETPTSHRMEN1KMT2A
SCHEMBL19879879 0.79 HPGD (0.60) L3MBTL1KEAP1MEN1KMT2AALDH1A1
SCHEMBL10517984 0.78 ALDH1A1 (0.51) L3MBTL1CETPMEN1RAB9AKMT2A
SCHEMBL4629040 0.77 CA1 (0.53) L3MBTL1
SCHEMBL2087952 0.75 CETP (0.67) L3MBTL1CETPTSHRMEN1RAB9A
SCHEMBL5706504 0.75 CETP (0.71) L3MBTL1CETPTSHRMEN1RAB9A
SCHEMBL9122853 0.73 KMT2A (0.47) L3MBTL1KEAP1MEN1RAB9AKMT2A
SCHEMBL27776504 0.73 CETP (0.51) L3MBTL1CETPTSHRMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1251346-B1 Sensors for the determination of organometallic compounds DYNASOL ELASTOMEROS SA (ES) 2008-10-15 EP claimed
EP-1251346-A1 Sensors for the determination of organometallic compounds Dynasol Elastomeros, S.A. (ES) 2002-10-23 EP claimed
US-20020151081-A1 Sensors for the determination of organometallic compounds DYNASOL ELASTOMEROS, S.A. 2002-10-17 US claimed
EP-1251346-B1 Sensors for the determination of organometallic compounds DYNASOL ELASTOMEROS SA (ES) 2008-10-15 EP disclosed
US-6875615-B2 Sensors for the determination of organometallic compounds DYNASOL ELASTOMEROS, S.A. (ES) 2005-04-05 US disclosed
EP-1251346-A1 Sensors for the determination of organometallic compounds Dynasol Elastomeros, S.A. (ES) 2002-10-23 EP disclosed
EP-1251346-A1 Sensors for the determination of organometallic compounds Dynasol Elastomeros, S.A. (ES) 2002-10-23 EP disclosed
US-20020151081-A1 Sensors for the determination of organometallic compounds DYNASOL ELASTOMEROS, S.A. 2002-10-17 US disclosed