Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | CETP | P11597 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659435 | 0.85 | ALDH1A1 (0.45) | ALDH1A1RAB9AKDM4EALOX12CETP | |
| SCHEMBL7089699 | 0.82 | RAB9A (0.71) | ALDH1A1RAB9AKDM4EALOX12CETP | |
| SCHEMBL1274654 | 0.81 | L3MBTL1 (0.65) | ALDH1A1RAB9AKDM4ECETPLMNA | |
| SCHEMBL4250189 | 0.81 | RAB9A (0.50) | ALDH1A1RAB9AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL3774635 | 0.80 | CETP (0.59) | ALDH1A1CETPSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL4610229 | 0.78 | L3MBTL1 (0.52) | ALDH1A1RAB9AKDM4ECETPLMNA | |
| SCHEMBL9847039 | 0.76 | LMNA (0.42) | ALDH1A1RAB9AKDM4EALOX12CETP | |
| SCHEMBL5706504 | 0.76 | CETP (0.71) | ALDH1A1RAB9AKDM4EALOX12CETP | |
| SCHEMBL13726222 | 0.74 | RIPK1 (0.74) | ALDH1A1LMNASMN1; SMN2RIPK1MAPT | |
| SCHEMBL14631798 | 0.74 | SMN1; SMN2 (0.56) | ALDH1A1RAB9AKDM4EALOX12CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326526-A1 | Aminoketones of substituted dibenzo- and pyridobenzo-azepinones and pharmaceutical compositions | ISTITUTO DE ANGELI S.p.A. (IT) | 1989-08-02 | — | — | EP | disclosed |