Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462923 | 0.82 | GPR119 (0.40) | GPR119CHRM4EPHX2SMN1; SMN2 | |
| SCHEMBL13588568 | 0.82 | HTR2C (0.38) | HTR2CHRH3AKR1C3HTR2ASMN1; SMN2 | |
| SCHEMBL14261373 | 0.78 | HTR2C (0.38) | HTR2CCHRM4HRH3AKR1C3HTR2A | |
| SCHEMBL387876 | 0.75 | GPR119 (0.71) | GPR119 | |
| SCHEMBL13548532 | 0.73 | EPHX2 (0.38) | GPR119CHRM4EPHX2 | |
| SCHEMBL470574 | 0.72 | GPR119 (0.45) | GPR119 | |
| SCHEMBL13548503 | 0.70 | SCD5 (0.36) | GPR119CHRM4EPHX2HTR2ADPP4 | |
| SCHEMBL38663614 | 0.70 | ALDH1A1 (0.52) | CHRM4SMN1; SMN2 | |
| SCHEMBL26529969 | 0.70 | CHRM2 (0.52) | GPR119SMN1; SMN2 | |
| SCHEMBL23260550 | 0.69 | CHRM2 (0.47) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |