SCHEMBL4611268

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL908287	0.82	CES2 (0.46)	AKR1B1LMNAGAATSHRKDM4E
	SCHEMBL299357	0.80	GAA (0.47)	AKR1B1LMNAGAATSHRKDM4E
	SCHEMBL25327233	0.78	THRB (0.46)	AKR1B1LMNAGAATSHRKDM4E
	SCHEMBL26729959	0.78	HDAC1 (0.44)	HDAC1HDAC6AKR1B1LMNAGAA
	SCHEMBL2728544	0.78	GAA (0.50)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL30192663	0.78	GAA (0.50)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL1000775	0.77	GABRP (0.47)	GABRPGABRDGABRA1GABRB1GABRG2
	Methane SCHEMBL28521569	0.76	GAA (0.48)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL583915	0.75	AKR1B1 (0.60)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL29009790	0.75	RXRA (0.50)	AKR1B1LMNAGAATSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.