Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 17/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 14/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSPO | P30536 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27877180 | 0.91 | FFAR1 (0.48) | FFAR1FFAR4HPGDCYP2C19 | |
| SCHEMBL2298577 | 0.81 | AKR1B1 (0.43) | FFAR1FFAR4HPGDCYP2C19POLB | |
| SCHEMBL1000871 | 0.81 | HPGD (0.55) | FFAR1FFAR4HPGDCYP2C19POLB | |
| SCHEMBL2397247 | 0.81 | FFAR1 (0.59) | FFAR1FFAR4POLBTSPODRD3 | |
| SCHEMBL30637597 | 0.81 | FFAR1 (0.59) | FFAR1FFAR4POLBTSPODRD3 | |
| SCHEMBL27550898 | 0.81 | CHRNA7 (0.40) | FFAR1FFAR4HPGDCYP2C19 | |
| SCHEMBL22300571 | 0.80 | CHRNA7 (0.39) | FFAR1FFAR4HPGDCYP2C19POLB | |
| SCHEMBL437626 | 0.80 | CHRNA7 (0.64) | FFAR1FFAR4POLB | |
| Hydrochloric Acid SCHEMBL30461911 | 0.80 | FFAR1 (0.58) | FFAR1FFAR4POLBTSPODRD3 | |
| SCHEMBL23665866 | 0.79 | HPGD (0.53) | FFAR1FFAR4HPGDCYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237872-B1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2008-02-27 | — | — | EP | disclosed |
| EP-1237872-A4 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20050042274-A1 | Compounds and compositions for delivering active agents | MHR INSTITUTIONAL PARTNERS IIA LP | 2005-02-24 | — | — | US | disclosed |
| US-6693208-B2 | AMINO ACIDS WHICH DELIVER ACTIVE AGENTS TO SELECTED BIOLOGICAL SYSTEMS IN INCREASED OR IMPROVED BIOAVAILABILITY | EMISPHERE TECHNOLOGIES, INC. | 2004-02-17 | — | — | US | disclosed |
| US-20030216589-A1 | Compounds and compositions for delivering active agents | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2003-11-20 | — | — | US | disclosed |
| EP-1237872-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001044199-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2001-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216589-A1 | Compounds and compositions for delivering active agents | IDUA, ALG1, APOB | FFAR1 3020/4885FFAR4 2916/4885HPGD 2736/4885 |
| US-20050042274-A1 | Compounds and compositions for delivering active agents | SERPINB1, ELANE, MMP8 | FFAR1 3965/4885FFAR4 3841/4885HPGD 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.